143538-27-6
Chemical Structure
Bay-X-7195
- CAS No.: 143538-27-6
- Formula:C30H32O6S
- Molecular Weight:520.64
IUPAC Name: (S,Z)-4-((1-carboxy-6-(4-(4-phenoxybutoxy)phenyl)hex-4-en-3-yl)thio)benzoic acid
InChIKey: MHKAEITVUICXRN-BPGQXAFDSA-N
SMILES: O=C(O)C1=CC=C(S[C@@H](CCC(O)=O)/C=C\CC2=CC=C(OCCCCOC3=CC=CC=C3)C=C2)C=C1
Biological Activity: Bay-X-7195 is a CYS leukotriene 1 receptor (CYS LT1) antagonist. Bay-X-7195 shows an antagonistic action to LTD4-induced bronchoconstriction in vitro and in vivo. Bay-X-7195 can be used foe the study of allergic and asthmatic[1][2].
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Bay-X-7195 | Bay-X-7195 is a CYS leukotriene 1 receptor (CYS LT1) antagonist. Bay-X-7195 shows an antagonistic action to LTD4-induced bronchoconstriction in vitro and in vivo. Bay-X-7195 can be used foe the study of allergic and asthmatic. | |||||||||||||||||||||
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- [1]. Boulet LP, et al. Inhibitory effects of BAY x 7195, a CYS leukotriene 1 receptor antagonist, on allergen-induced asthmatic responses. Ann Allergy Asthma Immunol. 1997 Aug;79(2):155-61. [Content Brief]
- [2]. Tanaka H, et al. The effect of a novel leukotriene C4/D4 antagonist, BAY-x-7195, on experimental allergic reactions. Prostaglandins. 1995 Nov-Dec;50(5-6):269-85. [Content Brief]
Keywords