1435934-03-4
1435934-03-4
Chemical Structure
4-Pyridoxic acid-d3
- CAS No.: 1435934-03-4
- Formula:C8H6D3NO4
- Molecular Weight:186.18
IUPAC Name: 3-hydroxy-5-(hydroxymethyl)-2-(methyl-d3)isonicotinic acid
InChIKey: HXACOUQIXZGNBF-FIBGUPNXSA-N
SMILES: OC(C1=C(O)C(C([2H])([2H])[2H])=NC=C1CO)=O
Biological Activity: 4-Pyridoxic acid-d3 is the deuterium labeled 4-Pyridoxic acid. 4-Pyridoxic acid is a catabolic product of vitamin B6 which is excreted in the urine[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
4-Pyridoxic acid-d3 | 98.79% | 4-Pyridoxic acid-d3 is the deuterium labeled 4-Pyridoxic acid. 4-Pyridoxic acid is a catabolic product of vitamin B6 which is excreted in the urine. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
4-Pyridoxic acid (Standard) | 98.11% | 4-Pyridoxic acid (Standard) is the analytical standard of 4-Pyridoxic acid. This product is intended for research and analytical applications. 4-Pyridoxic acid is a catabolic product of vitamin B6 which is excreted in the urine. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
4-Pyridoxic acid | 99.82% | 4-Pyridoxic acid is an endogenous substrate of renal organic anion transporters (OAT1/3) and a catabolite of vitamin B6. 4-Pyridoxic acid is excreted through OAT1/3-mediated tubular active secretion, which can reflect OAT1/3 activity. Elevated plasma concentrations of 4-Pyridoxic acid are associated with decreased OAT1/3 activity in chronic kidney disease (CKD) and can be used as a biomarker to reflect the severity of knee osteoarthritis (KOA) and lumbar spondylosis (LS). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Sharma SK, et al. Determination of vitamin B6 vitamers and pyridoxic acid in biological samples. J Chromatogr. 1992 Jul 1;578(1):45-51. [Content Brief]
