145888-79-5
Chemical Structure
RAMB4
- CAS No.: 145888-79-5
- Formula:C19H13Cl4NO
- Molecular Weight:413.12
IUPAC Name: 3,5-bis((E)-3,4-dichlorobenzylidene)piperidin-4-one
InChIKey: GJPXGFGIFQWUOC-ACFHMISVSA-N
SMILES: O=C(/C(CNC/1)=C/C2=CC=C(Cl)C(Cl)=C2)C1=C\C3=CC(Cl)=C(C=C3)Cl
Biological Activity: RAMB4 is a ubiquitin-proteasome system (UPS)-stressor. RAMB4 inhibits ubiquitin-mediated protein degradation upstream of the 20S proteasomal catalytic activites. RAMB4 triggers a ubiquitin-proteasome-system (UPS)-stress response without affecting 20S proteasome catalytic activities. Anticancer activity[1].
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RAMB4 | 98.02% | RAMB4 is a ubiquitin-proteasome system (UPS)-stressor. RAMB4 inhibits ubiquitin-mediated protein degradation upstream of the 20S proteasomal catalytic activites. RAMB4 triggers a ubiquitin-proteasome-system (UPS)-stress response without affecting 20S proteasome catalytic activities. Anticancer activity. | ||||||||||||||||||||
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Keywords