1461756-61-5
1461756-61-5
Chemical Structure
D-DT/MIF-1-IN-1
- CAS No.: 1461756-61-5
- Formula:C12H10ClNO3
- Molecular Weight:251.67
InChIKey: QYSDTIIQXYXQBG-UHFFFAOYSA-N
SMILES: OC(C1=CC=C(O1)NCC2=CC=C(C=C2)Cl)=O
Biological Activity: D-DT/MIF-1-IN-1 (Compound 4h) is a non-competitive, non-covalent inhibitor of MIF-1 and D-DT, with IC50 values of 2.4 μM and 4.0 μM against D-DT, and an IC50 value of 9.8 μM against MIF-1. D-DT/MIF-1-IN-1 inhibits D-DT-induced phosphorylation of ERK and exerts antiproliferative activity in non-small cell lung cancer cells[1].
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D-DT/MIF-1-IN-1 | D-DT/MIF-1-IN-1 (Compound 4h) is a non-competitive, non-covalent inhibitor of MIF-1 and D-DT, with IC50 values of 2.4 μM and 4.0 μM against D-DT, and an IC50 value of 9.8 μM against MIF-1. D-DT/MIF-1-IN-1 inhibits D-DT-induced phosphorylation of ERK and exerts antiproliferative activity in non-small cell lung cancer cells. | |||||||||||||||||||||
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References
Keywords
