146672-58-4
146672-58-4
Chemical Structure
PAPA NONOate
- CAS No.: 146672-58-4
- Formula:C6H16N4O2
- Molecular Weight:176.22
IUPAC Name: N'-(3-aminopropyl)-N-hydroxy-N'-propylnitrous hydrazide
InChIKey: CXQCOPWRDNFJDZ-UHFFFAOYSA-N
SMILES: NCCCN(CCC)N(O)N=O
Biological Activity: PAPA NONOate is a NO donor with a NO release half-life of 77 min (22-25°C). PAPA NONOate may represent a potential research for impaired wound healing in diabetes by increasing the rate of collagen synthesis at the wound site[1][2][3].
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PAPA NONOate | 98.0% | PAPA NONOate is a NO donor with a NO release half-life of 77 min (22-25°C). PAPA NONOate may represent a potential research for impaired wound healing in diabetes by increasing the rate of collagen synthesis at the wound site. | ||||||||||||||||||||
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References
- [1]. Rössig L, et al. Nitric oxide inhibits caspase-3 by S-nitrosation in vivo. J Biol Chem. 1999 Mar 12;274(11):6823-6. [Content Brief]
- [2]. N Dashti, et al. Study of the effect of PAPA NONOate on the rate of diabetic wound healing. African Journal of Biotechnology. 2014.
- [3]. Keefer LK, et al. "NONOates" (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: convenient nitric oxide dosage forms. Methods Enzymol. 1996;268:281-93. [Content Brief]
Keywords
