149027-97-4
149027-97-4
Chemical Structure
PD 140376
- CAS. Nr.: 149027-97-4
- Formula:C33H40N4O5
- Molecular Weight:572.69
IUPAC Name: (S)-3-((R)-2-(((adamantan-2-yloxy)carbonyl)amino)-3-(1H-indol-3-yl)-2-methylpropanamido)-4-(4-aminophenyl)butanoic acid
InChIKey: ADYHBZJCWPIGJS-FPRYDEEZSA-N
SMILES: O=C(C[C@H](CC1=CC=C(C=C1)N)NC([C@@](C)(CC2=CNC3=C2C=CC=C3)NC(OC4C5CC(CC4C6)CC6C5)=O)=O)O
Biological Activity: PD 140376 is a potent antagonist for the cholecystokininB/gastrin receptor, with Ki values of 0.18 nM and 0.21 nM in guinea-pig cortex and gastric gland membranes, respectively[1].
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PD 140376 | PD 140376 is a potent antagonist for the cholecystokininB/gastrin receptor, with Ki values of 0.18 nM and 0.21 nM in guinea-pig cortex and gastric gland membranes, respectively. | |||||||||||||||||||||
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