151928-32-4
151928-32-4
Chemical Structure
WIN 66306
- CAS. Nr.: 151928-32-4
- Formula:C41H52N8O9
- Molecular Weight:800.90
InChIKey: BNPYZZVTLFIGQT-FAWZPQLUSA-N
SMILES: O=C(N1[C@@](C(NCC(N[C@H](C(NCC(N[C@@](C(NCC(N2)=O)=O)([H])[C@@H](C3=CC(C/C=C(C)\C)=C(C=C3)O)O)=O)=O)C(C)C)=O)=O)([H])CCC1)[C@@H]2CC4=CNC5=CC=CC=C45
Biological Activity: WIN 66306 is a cyclic heptapeptide that can be isolated from an Aspergillus species. WIN 66306 is a neurokinin antagonist with antagonistic effects on both NK1 and NK2 receptors[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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WIN 66306 | 99.2% | WIN 66306 is a cyclic heptapeptide that can be isolated from an Aspergillus species. WIN 66306 is a neurokinin antagonist with antagonistic effects on both NK1 and NK2 receptors. | ||||||||||||||||||||
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References
- [1]. Barrow CJ, et al. WIN 66306, a new neurokinin antagonist produced by an Aspergillus species: fermentation, isolation and physico-chemical properties. J Antibiot (Tokyo). 1994 Nov;47(11):1182-7. [Content Brief]
- [2]. Barrow C J, et al. Structure, determination, pharmacological evaluation, and structure-activity studies of a new cyclic peptide substance P antagonist containing the new amino acid 3-prenyl-. beta.-hydroxytyrosine isolated from Aspergillus flavipes[J]. Journal of medicinal chemistry, 1994, 37(3): 356-363. [Content Brief]
Keywords
