153655-35-7
Chemical Structure
BM 170249
- CAS No.: 153655-35-7
- Formula:C14H22Cl4O4
- Molecular Weight:396.13
IUPAC Name: 2,2,13,13-tetrachlorotetradecanedioic acid
InChIKey: ZJDPSSMMBWOBMC-UHFFFAOYSA-N
SMILES: O=C(O)C(Cl)(Cl)CCCCCCCCCCC(Cl)(Cl)C(O)=O
Biological Activity: BM 170249 is a peroxisome proliferator, particularly in the perivenous region of the central acini in the liver. BM 170249 significantly reduces serum triglyceride and cholesterol levels in rats. BM 170249 strongly induces the activity of key enzymes in the peroxisome fatty acid β-oxidation system (such as acyl-CoA oxidase AOX, multifunctional enzyme PH, and thiolase PT), but leads to decreased activity of catalase and uricase in peroxisome components. BM 170249 could be used in lipid-lowering studies[1].
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BM 170249 | BM 170249 is a peroxisome proliferator, particularly in the perivenous region of the central acini in the liver. BM 170249 significantly reduces serum triglyceride and cholesterol levels in rats. BM 170249 strongly induces the activity of key enzymes in the peroxisome fatty acid β-oxidation system (such as acyl-CoA oxidase AOX, multifunctional enzyme PH, and thiolase PT), but leads to decreased activity of catalase and uricase in peroxisome components. BM 170249 could be used in lipid-lowering studies. | |||||||||||||||||||||
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Keywords
