154978-38-8
Chemical Structure
BAY-u 9773
- CAS No.: 154978-38-8
- Formula:C27H36O5S
- Molecular Weight:472.64
IUPAC Name: 4-(((4S,5R,6E,8E,10Z,13Z)-1-carboxy-4-hydroxynonadeca-6,8,10,13-tetraen-5-yl)thio)benzoic acid
InChIKey: PKJINWOACFYDQN-RBVMPENBSA-N
SMILES: OC(CCC[C@H](O)[C@@H](/C=C/C=C/C=C\C/C=C\CCCCC)SC1=CC=C(C=C1)C(O)=O)=O
Biological Activity: BAY-u 9773 is a selective cysteinyl-leukotriene receptor antagonist. BAY-u 9773 competitively antagonizes cysteinyl-leukotriene-induced contractions at typical and atypical cysteinyl-leukotriene receptors with comparable activity. BAY-u 9773 can be used for the research of trichomoniasis[1][2].
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BAY-u 9773 | BAY-u 9773 is a selective cysteinyl-leukotriene receptor antagonist. BAY-u 9773 competitively antagonizes cysteinyl-leukotriene-induced contractions at typical and atypical cysteinyl-leukotriene receptors with comparable activity. BAY-u 9773 can be used for the research of trichomoniasis. | |||||||||||||||||||||
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- [1]. Tudhope SR, et al. BAY u9773, a novel antagonist of cysteinyl-leukotrienes with activity against two receptor subtypes. Eur J Pharmacol. 1994;264(3):317-323. [Content Brief]
- [2]. Lee YA, et al. Trichomonas vaginalis-secreted cysteinyl leukotrienes promote migration, degranulation and MCP-1 production in mast cells. Parasite Immunol. 2020;42(12):e12789. [Content Brief]
Keywords
