1556861-34-7
1556861-34-7
Chemical Structure
STAT3-IN-52
- CAS No.: 1556861-34-7
- Formula:C20H20N4O4S
- Molecular Weight:412.46
InChIKey: OESYHAALOVZISZ-UHFFFAOYSA-N
SMILES: O=S(C(C=CC=C1C(C(NC2=CC=CC=C2N3CCNCC3)=C4)=O)=C1C4=O)(N)=O
Biological Activity: STAT3-IN-52 is an orally active STAT3 inhibitor with a Ki value of 2.42 μM. STAT3-IN-52 binds directly and selectively to the pY705 site of STAT3 (Ki = 0.44 μM), thereby impairing its function. STAT3-IN-52 induces apoptosis and triggers anti-tumor responses in vivo. STAT3-IN-52 can be used in breast cancer-related research[1].
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STAT3-IN-52 | STAT3-IN-52 is an orally active STAT3 inhibitor with a Ki value of 2.42 μM. STAT3-IN-52 binds directly and selectively to the pY705 site of STAT3 (Ki = 0.44 μM), thereby impairing its function. STAT3-IN-52 induces apoptosis and triggers anti-tumor responses in vivo. STAT3-IN-52 can be used in breast cancer-related research. | |||||||||||||||||||||
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References
Keywords
