1557137-61-7
1557137-61-7
Chemical Structure
UBA6-IN-1
- CAS No.: 1557137-61-7
- Formula:C20H21N5O4S
- Molecular Weight:427.48
InChIKey: KVEKKARIAOXGPM-IYOUNJFTSA-N
SMILES: NS(OC[C@@H]1C[C@H](C[C@@H]1O)N2C3=NC=NC(C4=CC5=CC=CC=C5N4)=C3C=C2)(=O)=O
Biological Activity: UBA6-IN-1 is a UBA6/UBE1L2 inhibitor (IC50 ≤50 nM) that acts by reducing the level of squalene epoxidase (SQLE). UBA6-IN-1 affects SREBP-dependent lipid metabolism processes and downstream cholesteryl ester transport, and can be used for cancer research[1].
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UBA6-IN-1 | UBA6-IN-1 is a UBA6/UBE1L2 inhibitor (IC50 ≤50 nM) that acts by reducing the level of squalene epoxidase (SQLE). UBA6-IN-1 affects SREBP-dependent lipid metabolism processes and downstream cholesteryl ester transport, and can be used for cancer research. | |||||||||||||||||||||
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References
Keywords
