1613711-28-6
1613711-28-6
Chemical Structure
SIK2-IN-5
- CAS No.: 1613711-28-6
- Formula:C23H23F2N5O3S
- Molecular Weight:487.52
InChIKey: NIFLRVAYOHHDFN-UHFFFAOYSA-N
SMILES: O=S(N1CCC(CC1)N2N=CC(C3=CN=C4NC=C(C5=CC(F)=CC(F)=C5OC)C4=C3)=C2)(C)=O
Biological Activity: SIK2-IN-5 is a SIK family kinase inhibitor, with IC50 values of 0.1-1 μM against SIK2 and SIK3, and an IC50 value of >1 μM against SIK1. SIK2-IN-5 inhibits the kinase activities of SIK1, SIK2 and SIK3. SIK2-IN-5 can be used in the research of ovarian cancer and breast cancer[1].
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SIK2-IN-5 | SIK2-IN-5 is a SIK family kinase inhibitor, with IC50 values of 0.1-1 μM against SIK2 and SIK3, and an IC50 value of >1 μM against SIK1. SIK2-IN-5 inhibits the kinase activities of SIK1, SIK2 and SIK3. SIK2-IN-5 can be used in the research of ovarian cancer and breast cancer. | |||||||||||||||||||||
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References
Keywords
