161503-98-6
Chemical Structure
5’-O-DMTr-3’-deoxyuridine 2’-CED phosphoramidite
- CAS No.: 161503-98-6
- Formula:C39H47N4O8P
- Molecular Weight:730.79
IUPAC Name: (2R,3R,5S)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChIKey: JKOUJIFQTRDOKR-MVFNBKNKSA-N
SMILES: O=C(C=CN1[C@H]2[C@H](OP(N(C(C)C)C(C)C)OCCC#N)C[C@@H](COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)O2)NC1=O
Biological Activity: 5’-O-DMTr-3’-deoxyuridine 2’-CED phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5’-O-DMTr-3’-deoxyuridine 2’-CED phosphoramidite | 5’-O-DMTr-3’-deoxyuridine 2’-CED phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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