162478-50-4
Chemical Structure
Aurantimycin A
- CAS No.: 162478-50-4
- Formula:C38H64N8O14
- Molecular Weight:856.96
IUPAC Name: (R)-N-((4aR,7S,16aS,19R,22S,23S)-6,18-dihydroxy-22-isopropyl-7-(methoxymethyl)-19-methyl-5,8,11,17,20,24-hexaoxodocosahydro-13H,22H-dipyridazino[6,1-f:6',1'-o][1]oxa[4,7,10,13,16]pentaazacyclononadecin-23-yl)-2-hydroxy-2-((2S,5S,6S)-2-hydroxy-5-isobutyl-6
InChIKey: JSVPJXYQXDNLRD-NSCUIBACSA-N
SMILES: C[C@H]1[C@H](CC(C)C)CC[C@]([C@](C(N[C@H]2[C@H](C(C)C)OC([C@@H](C)N(O)C([C@@H]3CCCNN3C(CNC([C@H](COC)N(O)C([C@H]4CCCNN4C2=O)=O)=O)=O)=O)=O)=O)(O)C)(O)O1
Biological Activity: Aurantimycin A (Adipogen), a depsipeptide antibiotic, displays strong activity against Gram-positive bacteria. Aurantimycin A is a substrate of the LieAB transporter[1][2].
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Aurantimycin A | Aurantimycin A (Adipogen), a depsipeptide antibiotic, displays strong activity against Gram-positive bacteria. Aurantimycin A is a substrate of the LieAB transporter. | |||||||||||||||||||||
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- [1]. U Gräfe, et al. Aurantimycins, new depsipeptide antibiotics from Streptomyces aurantiacus IMET 43917. Production, isolation, structure elucidation, and biological activity. J Antibiot (Tokyo). 1995 Feb;48(2):119-25. [Content Brief]
- [2]. Samuel Hauf, et al.Aurantimycin resistance genes contribute to survival of Listeria monocytogenes during life in the environment. Mol Microbiol. 2019 Apr;111(4):1009-1024. [Content Brief]
Keywords
