1627900-41-7
1627900-41-7
Chemical Structure
JNJ-54166060
- CAS No.: 1627900-41-7
- Formula:C20H15ClF4N4O
- Molecular Weight:438.81
IUPAC Name: (R)-(2-chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-1,4,6,7-tetrahydro-5H-imidazo[4,5-c]pyridin-5-yl)methanone
InChIKey: PLIXFSPGDVKMDM-LLVKDONJSA-N
SMILES: O=C(C1=CC=CC(C(F)(F)F)=C1Cl)N2CCC3=C(N=CN3C4=NC=C(F)C=C4)[C@H]2C
Biological Activity: JNJ-54166060 is a potent and selective P2X7 receptor antagonist, with IC50s of 4/115/72 nM for human/rat/mouse P2X7 receptor, respectively[1].
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JNJ-54166060 | JNJ-54166060 is a potent and selective P2X7 receptor antagonist, with IC50s of 4/115/72 nM for human/rat/mouse P2X7 receptor, respectively. | |||||||||||||||||||||
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