1632250-50-0

PF-06446846 hydrochloride Chemical Structure
1632250-50-0

Chemical Structure

PF-06446846 hydrochloride

  • CAS No.: 1632250-50-0
  • Formula:C22H21Cl2N7O
  • Molecular Weight:470.35

IUPAC Name: (R)-4-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)-N-(3-chloropyridin-2-yl)-N-(piperidin-3-yl)benzamide hydrochloride

InChIKey: AQSJYIVIWBIHOU-UNTBIKODSA-N

SMILES: O=C(N(C1=NC=CC=C1Cl)[C@H]2CNCCC2)C3=CC=C(N4N=NC5=CC=CN=C54)C=C3.[H]Cl

Biological Activity: PF-06446846 hydrochloride is an orally active and highly selective inhibitor of translation of Proprotein convertase subtilisin/kexin type 9 (PCSK9). PF-06446846 hydrochloride inhibits PCSK9 by inducing the ribosome to stall around codon 34[1].

Cat. No. Product Name Purity Description Pricing
HY-120088A
PF-06446846 hydrochloride 99.44% PF-06446846 hydrochloride is an orally active and highly selective inhibitor of translation of Proprotein convertase subtilisin/kexin type 9 (PCSK9). PF-06446846 hydrochloride inhibits PCSK9 by inducing the ribosome to stall around codon 34.
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