163837-48-7
Chemical Structure
(S)-Cetirizine dihydrochloride
Synonym(s): (S)-P071
- CAS No.: 163837-48-7
- Formula:C21H27Cl3N2O3
- Molecular Weight:461.81
IUPAC Name: (S)-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetic acid dihydrochloride
InChIKey: PGLIUCLTXOYQMV-FGJQBABTSA-N
SMILES: OC(COCCN(CC1)CCN1[C@@H](C2=CC=CC=C2)C3=CC=C(C=C3)Cl)=O.Cl.Cl
Biological Activity: (S)-Cetirizine dihydrochloride ((S)-P071) is an orally active antagonist of the histamine H1 receptor with a Ki value of 39.1 nM. (S)-Cetirizine dihydrochloride exerts anti-allergic activity by binding to the histamine H1 receptor and blocking the action of histamine. (S)-Cetirizine dihydrochloride is promising for research of allergic diseases such as allergic rhinitis[1].
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(S)-Cetirizine dihydrochloride | (S)-Cetirizine dihydrochloride ((S)-P071) is an orally active antagonist of the histamine H1 receptor with a Ki value of 39.1 nM. (S)-Cetirizine dihydrochloride exerts anti-allergic activity by binding to the histamine H1 receptor and blocking the action of histamine. (S)-Cetirizine dihydrochloride is promising for research of allergic diseases such as allergic rhinitis. | |||||||||||||||||||||
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Keywords
