1643609-75-9
1643609-75-9
Chemical Structure
BIBU1361 dihydrochloride
- CAS No.: 1643609-75-9
- Formula:C22H29Cl3FN7
- Molecular Weight:516.87
IUPAC Name: N-(3-chloro-4-fluorophenyl)-6-(4-((diethylamino)methyl)piperidin-1-yl)pyrimido[5,4-d]pyrimidin-4-amine dihydrochloride
InChIKey: ZNNWCQCQUKAMGL-UHFFFAOYSA-N
SMILES: CCN(CC1CCN(C2=NC3=C(NC4=CC=C(F)C(Cl)=C4)N=CN=C3C=N2)CC1)CC.Cl.Cl
Biological Activity: BIBU1361 dihydrochloride induces apoptosis and inhibits autophagy. BIBU1361 inhibits pro-survival pathways Akt/mTOR and gp130/JAK/STAT3, and decreased levels of pro-inflammatory cytokine IL-6[1].
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BIBU1361 dihydrochloride | BIBU1361 dihydrochloride induces apoptosis and inhibits autophagy. BIBU1361 inhibits pro-survival pathways Akt/mTOR and gp130/JAK/STAT3, and decreased levels of pro-inflammatory cytokine IL-6. | |||||||||||||||||||||
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