167354-91-8
Chemical Structure
(+/-)13-HODE cholesteryl ester
- CAS 番号: 167354-91-8
- Formula:
- Molecular Weight:665.08
IUPAC Name: (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (9Z,11E)-13-hydroxyoctadeca-9,11-dienoate
InChIKey: RZXYPSUQZUUHPD-ZCNQQENXSA-N
SMILES: CCCCCC(O)/C=C/C=C\CCCCCCCC(O[C@H]1CC[C@]2(C)[C@@]3([H])CC[C@@]4(C)[C@](CC[C@]4([H])[C@@H](CCCC(C)C)C)([H])[C@]3([H])CC=C2C1)=O
Biological Activity: (±)13-HODE cholesteryl ester is originally extracted from atherosclerotic lesions1 and shown to be produced by Cu2+-catalyzed oxidation of LDL. Later studies determined that 15-LO from rabbit reticulocytes and human monocytes were able to metabolize cholesteryl linoleate, a major component of LDL, to 13-HODE cholesteryl ester.
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(+/-)13-HODE cholesteryl ester | (±)13-HODE cholesteryl ester is originally extracted from atherosclerotic lesions1 and shown to be produced by Cu2+-catalyzed oxidation of LDL. Later studies determined that 15-LO from rabbit reticulocytes and human monocytes were able to metabolize cholesteryl linoleate, a major component of LDL, to 13-HODE cholesteryl ester. | |||||||||||||||||||||
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