16869-42-4
16869-42-4
Chemical Structure
Gamma-Glu-Abu
- CAS No.: 16869-42-4
- Formula:C9H16N2O5
- Molecular Weight:232.23
InChIKey: FUZOZPRKGAXGOB-WDSKDSINSA-N
SMILES: OC([C@@H](N)CCC(N[C@@H](CC)C(O)=O)=O)=O
Biological Activity: Gamma-Glu-Abu is a CaSR activator with an EC50 of 0.21 μM (in HEK-293 cells). Gamma-Glu-Abu interacts with the extracellular venus flytrap domain of hCaSR via its N-terminal γ-L-glutamyl residue, the neutral aliphatic side chain of the Abu residue, and the C-terminal carboxylic acid group[1].
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Gamma-Glu-Abu | Gamma-Glu-Abu is a CaSR activator with an EC50 of 0.21 μM (in HEK-293 cells). Gamma-Glu-Abu interacts with the extracellular venus flytrap domain of hCaSR via its N-terminal γ-L-glutamyl residue, the neutral aliphatic side chain of the Abu residue, and the C-terminal carboxylic acid group. | |||||||||||||||||||||
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