172489-10-0
172489-10-0
Chemical Structure
KR-30450
Synonym(s): SKP 450
- CAS No.: 172489-10-0
- Formula:C17H18N2O6
- Molecular Weight:346.33
IUPAC Name: (R)-1-(2-(1,3-dioxolan-2-yl)-2-methyl-6-nitro-2H-chromen-4-yl)pyrrolidin-2-one
InChIKey: NJJPKIPOZSWUHV-QGZVFWFLSA-N
SMILES: O=C1N(C2=C[C@](C)(C3OCCO3)OC4=CC=C([N+]([O-])=O)C=C24)CCC1
Biological Activity: KR-30450 (SKP 450) is a potent K+ATP opener, and a potassium channel activator. KR-30450 exerts more potent cardioprotective effects than Lemakalim (HY-14255). KR-30450 significantly improves reperfusion cardiac function. KR-30450 significantly attenuates reperfusion contracture and lactate dehydrogenase release[1].
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KR-30450 | KR-30450 (SKP 450) is a potent K+ATP opener, and a potassium channel activator. KR-30450 exerts more potent cardioprotective effects than Lemakalim (HY-14255). KR-30450 significantly improves reperfusion cardiac function. KR-30450 significantly attenuates reperfusion contracture and lactate dehydrogenase release. | |||||||||||||||||||||
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