173399-03-6
Chemical Structure
Aliskiren hydrochloride
Synonym(s): CGP 60536 hydrochloride; CGP60536B hydrochloride; SPP 100 hydrochloride
- CAS No.: 173399-03-6
- Formula:C30H54ClN3O6
- Molecular Weight:588.22
IUPAC Name: (2S,4S,5S,7S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-2-isopropyl-7-(4-methoxy-3-(3-methoxypropoxy)benzyl)-8-methylnonanamide hydrochloride
InChIKey: BSJUIBZAXCXFMZ-NATPOTRJSA-N
SMILES: [H]Cl.COCCCOC1=CC(C[C@@H](C[C@@H]([C@H](C[C@H](C(NCC(C)(C(N)=O)C)=O)C(C)C)O)N)C(C)C)=CC=C1OC
Biological Activity: Aliskiren (CGP 60536; CGP60536B; SPP 100) hydrochloride is an orally active and selective renin inhibitor, with IC50 of 1.5 nM. Aliskiren hydrochloride can be used for the research of hypertension, cardiovascular diseases and cancer cachexia[1]-[4].
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Aliskiren hydrochloride | Aliskiren (CGP 60536; CGP60536B; SPP 100) hydrochloride is an orally active and selective renin inhibitor, with IC50 of 1.5 nM. Aliskiren hydrochloride can be used for the research of hypertension, cardiovascular diseases and cancer cachexia-. | |||||||||||||||||||||
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Aliskiren-d6 hydrochloride | Aliskiren-d6 (hydrochloride) is is deuterium labeled Aliskiren, which is a direct renin inhibitor. | |||||||||||||||||||||
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