179120-92-4
Chemical Structure
Altinicline
Synonym(s): SIB-1508Y free base
- CAS No.: 179120-92-4
- Formula:C12H14N2
- Molecular Weight:186.26
IUPAC Name: (S)-3-ethynyl-5-(1-methylpyrrolidin-2-yl)pyridine
InChIKey: NUPUDYKEEJNZRG-LBPRGKRZSA-N
SMILES: CN1[C@@H](CCC1)C=2C=C(C#C)C=NC2
Biological Activity: Altinicline (SIB-1508Y free base) is a selective α4β2 nicotinic acetylcholine receptor (nAChR) agonist, with no activity against α7 or α1β1γδ nAChRs and only extremely low activity against α3β4 nAChRs. Altinicline reverses escape deficits and increases avoidance responses. Altinicline is applicable to research related to depression[1].
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Altinicline | Altinicline (SIB-1508Y free base) is a selective α4β2 nicotinic acetylcholine receptor (nAChR) agonist, with no activity against α7 or α1β1γδ nAChRs and only extremely low activity against α3β4 nAChRs. Altinicline reverses escape deficits and increases avoidance responses. Altinicline is applicable to research related to depression. | |||||||||||||||||||||
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Keywords
