1802891-23-1
Chemical Structure
(S)-Human enteropeptidase-IN-1
- CAS No.: 1802891-23-1
- Formula:C20H18N4O7
- Molecular Weight:426.38
SMILES: O=C([C@@]1(CC(O)=O)CC(C2=CC=CC(OC(C3=CC=C(NC(N)=N)C=C3)=O)=C2)=NO1)O
Biological Activity: (S)-Human enteropeptidase-IN-1 (Compound 6c) is an orally active enteropeptidase inhibitor with low systemic exposure (IC50 (initial): 26 nM; IC50 (app): 1.8 nM). (S)-Human enteropeptidase-IN-1 promotes increased fecal protein output and effectively reduces body weight in a diet-induced obese (DIO) rat model. (S)-Human enteropeptidase-IN-1 inhibits enteropeptidase via a reversible covalent mechanism and prolongs the enzyme inactivation time. (S)-Human enteropeptidase-IN-1 can be used in anti-obesity research[1].
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(S)-Human enteropeptidase-IN-1 | (S)-Human enteropeptidase-IN-1 (Compound 6c) is an orally active enteropeptidase inhibitor with low systemic exposure (IC50 (initial): 26 nM; IC50 (app): 1.8 nM). (S)-Human enteropeptidase-IN-1 promotes increased fecal protein output and effectively reduces body weight in a diet-induced obese (DIO) rat model. (S)-Human enteropeptidase-IN-1 inhibits enteropeptidase via a reversible covalent mechanism and prolongs the enzyme inactivation time. (S)-Human enteropeptidase-IN-1 can be used in anti-obesity research. | |||||||||||||||||||||
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Keywords
