1818339-66-0
1818339-66-0
Chemical Structure
PF-06751979
- CAS No.: 1818339-66-0
- Formula:C18H19F2N5O3S2
- Molecular Weight:455.50
IUPAC Name: N-(2-((4aR,6S,8aR)-2-amino-6-methyl-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl)thiazol-4-yl)-5-(difluoromethoxy)picolinamide
InChIKey: ZLZUHACSRMOLLV-RAALSFIWSA-N
SMILES: FC(F)OC1=CN=C(C(NC2=CSC([C@]34CO[C@@H](C)C[C@@]3([H])CSC(N)=N4)=N2)=O)C=C1
Biological Activity: PF-06751979 is a potent, brain penetrant, β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 of 7.3 nM in BACE1 binding assay.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PF-06751979 | 99.57% | PF-06751979 is a potent, brain penetrant, β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 of 7.3 nM in BACE1 binding assay. | ||||||||||||||||||||
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Keywords
