1878200-88-4

IDO1/TDO-IN-9 Chemical Structure
1878200-88-4

Chemical Structure

IDO1/TDO-IN-9

  • CAS No.: 1878200-88-4
  • Formula:C6H3ClFN3O
  • Molecular Weight:187.56

SMILES: NC1=NOC2=NC(Cl)=C(F)C=C21

Biological Activity: IDO1/TDO-IN-9 (Compound 66) is a potent dual inhibitor targeting indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO) with IC50s of <1 μM. IDO1/TDO-IN-9 inhibits the activity of IDO1 and TDO, blocking tryptophan degradation to kynurenine, restoring immune activity in the tumor microenvironment, and suppressing tumor growth. IDO1/TDO-IN-9 is promising for research of cancers[1].

Cat. No. Product Name Purity Description Pricing
HY-177086 		IDO1/TDO-IN-9 99.54% IDO1/TDO-IN-9 (Compound 66) is a potent dual inhibitor targeting indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO) with IC50s of <1 μM. IDO1/TDO-IN-9 inhibits the activity of IDO1 and TDO, blocking tryptophan degradation to kynurenine, restoring immune activity in the tumor microenvironment, and suppressing tumor growth. IDO1/TDO-IN-9 is promising for research of cancers.
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