IDO1/TDO-IN-9
Based on 1 Customer Validation
IDO1/TDO-IN-9 (Compound 66) is a potent dual inhibitor targeting indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO) with IC50s of <1 μM. IDO1/TDO-IN-9 inhibits the activity of IDO1 and TDO, blocking tryptophan degradation to kynurenine, restoring immune activity in the tumor microenvironment, and suppressing tumor growth. IDO1/TDO-IN-9 is promising for research of cancers.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 99.54%
- CAS No.: 1878200-88-4
- Formule: C6H3ClFN3O
- Masse moléculaire:187.56
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
Chemical Information
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CAS No. 1878200-88-4
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Appearance Solid
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Masse moléculaire 187.56
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Formule C6H3ClFN3O
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Color Off-white to light brown
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SMILES
NC1=NOC2=NC(Cl)=C(F)C=C21
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (533.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.3316 mL | 26.6581 mL | 53.3163 mL | 133.2907 mL |
| 5 mM | 1.0663 mL | 5.3316 mL | 10.6633 mL | 26.6581 mL | |
| 10 mM | 0.5332 mL | 2.6658 mL | 5.3316 mL | 13.3291 mL | |
| 15 mM | 0.3554 mL | 1.7772 mL | 3.5544 mL | 8.8860 mL | |
| 20 mM | 0.2666 mL | 1.3329 mL | 2.6658 mL | 6.6645 mL | |
| 25 mM | 0.2133 mL | 1.0663 mL | 2.1327 mL | 5.3316 mL | |
| 30 mM | 0.1777 mL | 0.8886 mL | 1.7772 mL | 4.4430 mL | |
| 40 mM | 0.1333 mL | 0.6665 mL | 1.3329 mL | 3.3323 mL | |
| 50 mM | 0.1066 mL | 0.5332 mL | 1.0663 mL | 2.6658 mL | |
| 60 mM | 0.0889 mL | 0.4443 mL | 0.8886 mL | 2.2215 mL | |
| 80 mM | 0.0666 mL | 0.3332 mL | 0.6665 mL | 1.6661 mL | |
| 100 mM | 0.0533 mL | 0.2666 mL | 0.5332 mL | 1.3329 mL |
IDO1/TDO-IN-9 Related Classifications
HY-177086 Related Classifications
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