1884574-15-5
1884574-15-5
Chemical Structure
RdRP-IN-11
- CAS No.: 1884574-15-5
- Formula:C25H20N2O5S2
- Molecular Weight:492.56
IUPAC Name: 5-(5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl)-4-methoxy-2-methyl-N-(quinolin-8-ylsulfonyl)benzamide
InChIKey: IGHQXATTWZGDIH-UHFFFAOYSA-N
SMILES: O=C(NS(=O)(=O)C1=CC=CC2=CC=CN=C21)C3=CC(=C(OC)C=C3C)C=4SC(C#CCO)=CC4
Biological Activity: RdRP-IN-11 is a non-nucleoside dengue virus RNA-dependent RNA polymerase (RdRp) inhibitor that binds to the palm subdomain of DENV NS5 RdRp, with an IC50 of 23 nM and a Kd of 7 nM. RdRP-IN-11 exhibits antiviral activity against all four dengue serotypes. RdRP-IN-11 can be used for dengue-related research[1].
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RdRP-IN-11 | RdRP-IN-11 is a non-nucleoside dengue virus RNA-dependent RNA polymerase (RdRp) inhibitor that binds to the palm subdomain of DENV NS5 RdRp, with an IC50 of 23 nM and a Kd of 7 nM. RdRP-IN-11 exhibits antiviral activity against all four dengue serotypes. RdRP-IN-11 can be used for dengue-related research. | |||||||||||||||||||||
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