1940128-37-9

IDH1 Inhibitor 5 Chemical Structure
1940128-37-9

Chemical Structure

IDH1 Inhibitor 5

  • CAS No.: 1940128-37-9
  • Formula:C26H34N4O3
  • Molecular Weight:450.57

IUPAC Name: ((1r,4r)-4-isopropoxycyclohexyl)(8-morpholino-5,11-dihydro-6H-benzo[b]pyrido[2,3-e][1,4]diazepin-6-yl)methanone

InChIKey: FFJIUZWEHCMKKS-XYWHTSSQSA-N

SMILES: CC(O[C@H]1CC[C@@H](CC1)C(N2CC3=C(NC4=C2C=C(C=C4)N5CCOCC5)N=CC=C3)=O)C

Biological Activity: IDH1 Inhibitor 5 (compound 2) is an IDH1 (isocitrate dehydrogenase 1) inhibitor. IDH1 Inhibitor 5 inhibits MOG cells and wild-type IDH1 glioma cells with expressing exogenous mutant IDH1 R132H protein with IC50s of 64.4 and 34.9 nM, respectively[1].

Cat. No. Product Name Purity Description Pricing
HY-143306 		IDH1 Inhibitor 5 IDH1 Inhibitor 5 (compound 2) is an IDH1 (isocitrate dehydrogenase 1) inhibitor. IDH1 Inhibitor 5 inhibits MOG cells and wild-type IDH1 glioma cells with expressing exogenous mutant IDH1 R132H protein with IC50s of 64.4 and 34.9 nM, respectively.
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