1947408-74-3
Chemical Structure
Cysteine thiol probe
- CAS No.: 1947408-74-3
- Formula:C11H12BrNO3S
- Molecular Weight:318.19
IUPAC Name: methyl (4-bromobenzoyl)-L-cysteinate
InChIKey: QLAHQHTYCQKQLI-VIFPVBQESA-N
SMILES: SC[C@@H](C(OC)=O)NC(C1=CC=C(Br)C=C1)=O
Biological Activity: Cysteine Thiol Probe is a thiol-based probe designed to label electrophilic natural products. Cysteine Thiol Probe possesses each of the characteristics of an ideal pharmacophore probe, and has a chromophore. Cysteine Thiol Probe is capable of engaging enone-, β-lactam-, and β-lactone-based electrophilic metabolites[1][2].
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Cysteine thiol probe | 98.55% | Cysteine Thiol Probe is a thiol-based probe designed to label electrophilic natural products. Cysteine Thiol Probe possesses each of the characteristics of an ideal pharmacophore probe, and has a chromophore. Cysteine Thiol Probe is capable of engaging enone-, β-lactam-, and β-lactone-based electrophilic metabolites. | ||||||||||||||||||||
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- [1]. Castro-Falcón G, et al. Thiol Probes To Detect Electrophilic Natural Products Based on Their Mechanism of Action. ACS Chem Biol. 2016 Aug 19;11(8):2328-36. [Content Brief]
- [2]. Reimer D, et al. Thiol-Based Probe for Electrophilic Natural Products Reveals That Most of the Ammosamides Are Artifacts. J Nat Prod. 2017 Jan 27;80(1):126-133. [Content Brief]
Keywords