1950628-94-0
1950628-94-0
Chemical Structure
TGFβRI-IN-1
- CAS No.: 1950628-94-0
- Formula:C20H14D3N5O2
- Molecular Weight:362.40
IUPAC Name: N-(4-(3-(5-(methoxy-d3)pyridin-2-yl)-1H-pyrrolo[3,2-b]pyridin-2-yl)pyridin-2-yl)acetamide
InChIKey: VRPRBQAJAQCSCW-BMSJAHLVSA-N
SMILES: CC(NC1=NC=CC(C(N2)=C(C3=NC=C(OC([2H])([2H])[2H])C=C3)C4=C2C=CC=N4)=C1)=O
Biological Activity: TGFβRI-IN-1 is an oral active and selective TGFβ receptor type I (TGFβRI) kinase inhibitor, with IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII, respectively[1] .
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TGFβRI-IN-1 | TGFβRI-IN-1 is an oral active and selective TGFβ receptor type I (TGFβRI) kinase inhibitor, with IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII, respectively . | |||||||||||||||||||||
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References
Keywords
