1. TGF-beta/Smad
  2. TGF-β Receptor
  3. TGFβRI-IN-1

TGFβRI-IN-1 

Cat. No.: HY-114192
Handling Instructions

TGFβRI-IN-1 is an oral active and selective TGFβ receptor type I (TGFβRI) kinase inhibitor, with IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII, respectively .

For research use only. We do not sell to patients.

TGFβRI-IN-1 Chemical Structure

TGFβRI-IN-1 Chemical Structure

CAS No. : 1950628-94-0

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Description

TGFβRI-IN-1 is an oral active and selective TGFβ receptor type I (TGFβRI) kinase inhibitor, with IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII, respectively[1] .

IC50 & Target

IC50: 2 nM (TGFβRI)[1].

Molecular Weight

362.40

Formula

C₂₀H₁₄D₃N₅O₂

CAS No.

1950628-94-0

SMILES

CC(NC1=NC=CC(C(N2)=C(C3=NC=C(OC([2H])([2H])[2H])C=C3)C4=C2C=CC=N4)=C1)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
TGFβRI-IN-1
Cat. No.:
HY-114192
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