1952264-36-6
Chemical Structure
ZEN-3411
- CAS No.: 1952264-36-6
- Formula:C21H20N4O2
- Molecular Weight:360.41
IUPAC Name: 6-(3,5-dimethylisoxazol-4-yl)-1-(4-(oxiran-2-yl)benzyl)-1H-benzo[d]imidazol-4-amine
InChIKey: XINQCOMOQIYWTG-UHFFFAOYSA-N
SMILES: NC1=CC(C2=C(C)ON=C2C)=CC3=C1N=CN3CC4=CC=C(C5OC5)C=C4
Biological Activity: ZEN-3411 is a BET inhibitor with IC50s of 0.05, 0.05 and 0.06 μM for BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2), respectively. ZEN-3411 can be used to form PROTACs to induce degradation of BRD4[1].
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ZEN-3411 | ZEN-3411 is a BET inhibitor with IC50s of 0.05, 0.05 and 0.06 μM for BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2), respectively. ZEN-3411 can be used to form PROTACs to induce degradation of BRD4. | |||||||||||||||||||||
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Keywords