1977493-48-3
1977493-48-3
Chemical Structure
m-PEG12-amine
- CAS No.: 1977493-48-3
- Formula:C25H53NO12
- Molecular Weight:559.69
IUPAC Name: 2,5,8,11,14,17,20,23,26,29,32,35-dodecaoxaheptatriacontan-37-amine
InChIKey: MSKSQCLPULZWNO-UHFFFAOYSA-N
SMILES: COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
Biological Activity: m-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG12-amine is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
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m-PEG12-amine | 99.71% | m-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. m-PEG12-amine is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | ||||||||||||||||||||
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References
- [1]. Vasco AV, et al. A Multicomponent Stapling Approach to Exocyclic Functionalized Helical Peptides: Adding Lipids, Sugars, PEGs, Labels, and Handles to the Lactam Bridge. Bioconjug Chem. 2019 Jan 16;30(1):253-259. [Content Brief]
- [2]. Joseph Fox, et al. Methods for inducing bioorthogonal reactivity. WO2017106427A1.
Keywords
