203051-01-8
Chemical Structure
CRM-51005
- CAS No.: 203051-01-8
- Formula:C15H20O3
- Molecular Weight:248.32
InChIKey: BEEZXTYOZYXCKI-JXMROGBWSA-N
SMILES: CCC/C=C(C1=C(C(O)=C(C(O)=C1)CC)C=O)\C
Biological Activity: CRM-51005 is a phospholipase C (PLC)γ1 inhibitor with a bovine IC50 of 13.0 μg/mL. CRM-51005 inhibits PLCγ1 enzymatic activity and platelet-derived growth factor-induced phosphoinositide turnover. CRM-51005 acts as a cell growth inhibitor via suppression of PLC, phosphoinositide turnover, DNA synthesis, and cell proliferation[1].
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CRM-51005 | CRM-51005 is a phospholipase C (PLC)γ1 inhibitor with a bovine IC50 of 13.0 μg/mL. CRM-51005 inhibits PLCγ1 enzymatic activity and platelet-derived growth factor-induced phosphoinositide turnover. CRM-51005 acts as a cell growth inhibitor via suppression of PLC, phosphoinositide turnover, DNA synthesis, and cell proliferation. | |||||||||||||||||||||
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