205514-29-0
205514-29-0
Chemical Structure
Quoromycin
- CAS. Nr.: 205514-29-0
- Formula:C12H8N2O2S
- Molecular Weight:244.27
IUPAC Name: 6-(phenylsulfonyl)nicotinonitrile
InChIKey: WLMRLYWAJRGRKR-UHFFFAOYSA-N
SMILES: N#CC1=CN=C(C=C1)S(=O)(=O)C=2C=CC=CC2
Biological Activity: Quoromycin is an orally active SmcR inhibitor with a Kd of 0.697 μM for Vibrio vulnificus SmcR. Quoromycin binds directly to SmcR, reduces its DNA-binding affinity, and inhibits the quorum sensing signaling pathway. Quoromycin is applicable to the research of Vibrio vulnificus infection[1].
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Quoromycin | Quoromycin is an orally active SmcR inhibitor with a Kd of 0.697 μM for Vibrio vulnificus SmcR. Quoromycin binds directly to SmcR, reduces its DNA-binding affinity, and inhibits the quorum sensing signaling pathway. Quoromycin is applicable to the research of Vibrio vulnificus infection. | |||||||||||||||||||||
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References
Keywords
