2068867-65-0
Chemical Structure
BAR-072
- CAS No.: 2068867-65-0
- Formula:C18H13N3O6
- Molecular Weight:367.31
InChIKey: UWGONYFTAALZSO-VXLYETTFSA-N
SMILES: O=C(C1=C(C=CC(O)=C1)O)N/N=C/C2=CC=C(O2)C3=CC=CC=C3[N+]([O-])=O
Biological Activity: BAR-072 is a small-molecule inhibitor targeting TraE, with a KD of 2.7 µM. It significantly inhibits the transfer of the antibiotic resistance-associated plasmid pKM101. BAR-072 shows promise as a candidate compound for blocking the spread of bacterial resistance genes and holds potential for research in infectious disease and antimicrobial resistance control[1].
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BAR-072 | BAR-072 is a small-molecule inhibitor targeting TraE, with a KD of 2.7 µM. It significantly inhibits the transfer of the antibiotic resistance-associated plasmid pKM101. BAR-072 shows promise as a candidate compound for blocking the spread of bacterial resistance genes and holds potential for research in infectious disease and antimicrobial resistance control. | |||||||||||||||||||||
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Keywords