2070015-20-0
Chemical Structure
Hydroxy Itraconazole-d8
Synonym(s): R-63373-d8
- CAS No.: 2070015-20-0
- Formula:C35H30D8Cl2N8O5
- Molecular Weight:729.68
IUPAC Name: 4-(4-(4-(4-((2-((1H-1,2,4-triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(3-hydroxybutan-2-yl-1,1,1,2,3,4,4,4-d8)-2,4-dihydro-3H-1,2,4-triazol-3-one
InChIKey: ISJVOEOJQLKSJU-QIKAZICUSA-N
SMILES: O=C1N(C(C([2H])([2H])[2H])([2H])C(O)([2H])C([2H])([2H])[2H])N=CN1C2=CC=C(N3CCN(C4=CC=C(OCC5OC(CN6N=CN=C6)(C7=CC=C(Cl)C=C7Cl)OC5)C=C4)CC3)C=C2
Biological Activity: Hydroxy Itraconazole-d8 is the deuterium labeled Hydroxy Itraconazole (HY-12772). Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Hydroxy Itraconazole-d8 | 99.71% | Hydroxy Itraconazole-d8 is the deuterium labeled Hydroxy Itraconazole (HY-12772). Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent. | ||||||||||||||||||||
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Hydroxy Itraconazole (Standard) | 99.63% | Levetiracetam (Standard) is the analytical standard of Levetiracetam. This product is intended for research and analytical applications. Levetiracetam, an antiepileptic agent, binds the synaptic vesicle protein SV2A. Levetiracetam enhances Temozolomide effect on glioblastoma stem cell proliferation and apoptosis. Levetiracetam modulates HDAC levels ultimately silencing MGMT, thus increasing Temozolomide effectiveness. A chemosensitizer agent. | ||||||||||||||||||||
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Hydroxy Itraconazole-d6 | Hydroxy Itraconazole-d6 (R-63373-d6) is deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole (Itraconazole metabolite Hydroxy Itraconazole; R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent. | |||||||||||||||||||||
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(2S)-Hydroxy Itraconazole-d8 | 99.9% | (2S)-Hydroxy Itraconazole-d8 ((2S)-R-63373-d8) is the enantiomer of Hydroxy Itraconazole-d8 (R-63373-d8) (HY-12772S). Hydroxy Itraconazole-d8 is the deuterium labeled Hydroxy Itraconazole (HY-12772). Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent. | ||||||||||||||||||||
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(2R,4S)-Hydroxy Itraconazole-d8 | (2R,4S)-Hydroxy Itraconazole-d8 is the deuterium labeled (2R,4S)-Hydroxy Itraconazole. | |||||||||||||||||||||
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(2R,4S)-Hydroxy Itraconazole-d5 | (2R,4S)-Hydroxy Itraconazole-d5 is the deuterium labeled (2R,4S)-Hydroxy Itraconazole. | |||||||||||||||||||||
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Hydroxy Itraconazole | 99.80% | Hydroxy Itraconazole (R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent. | ||||||||||||||||||||
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