2072145-74-3
Chemical Structure
2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-trifluoromethyluridine
- CAS No.: 2072145-74-3
- Formula:C20H18F4N2O7
- Molecular Weight:474.36
IUPAC Name: ((2R,3R,4S,5R)-4-acetoxy-5-(2,4-dioxo-5-(trifluoromethyl)-3,4-dihydropyrimidin-1(2H)-yl)-3-fluorotetrahydrofuran-2-yl)methyl 4-methylbenzoate
InChIKey: PGWKJLSXHOQROZ-KCYZZUKISA-N
SMILES: F[C@H]1[C@@H](OC(C)=O)[C@H](N2C(NC(C(C(F)(F)F)=C2)=O)=O)O[C@@H]1COC(C3=CC=C(C)C=C3)=O
Biological Activity: 2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-trifluoromethyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-trifluoromethyluridine | 2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-trifluoromethyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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