2086689-00-9
Chemical Structure
N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester)
- CAS No.: 2086689-00-9
- Formula:C26H48N4O10
- Molecular Weight:576.68
IUPAC Name: tert-butyl 1-azido-14-((3-(tert-butoxy)-3-oxopropoxy)methyl)-12-oxo-3,6,9,16-tetraoxa-13-azanonadecan-19-oate
InChIKey: MFAWTCNLWLJEKI-UHFFFAOYSA-N
SMILES: O=C(OC(C)(C)C)CCOCC(COCCC(OC(C)(C)C)=O)NC(CCOCCOCCOCCN=[N+]=[N-])=O
Biological Activity: N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) | N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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