209268-36-0
209268-36-0
Chemical Structure
S-5751
- CAS No.: 209268-36-0
- Formula:C25H31NO4S
- Molecular Weight:441.58
IUPAC Name: (Z)-7-((1R,2R,3S,5S)-2-(5-hydroxybenzo[b]thiophene-3-carboxamido)-6,6-dimethylbicyclo[3.1.1]heptan-3-yl)hept-5-enoic acid
InChIKey: ZXBHFWFKSIYJEK-MFJOXFORSA-N
SMILES: O=C(C(C1=C2)=CSC1=CC=C2O)N[C@H]3[C@@]4([H])C(C)([C@](C[C@@H]3C/C=C\CCCC(O)=O)([H])C4)C
Biological Activity: S-5751 is an orally active prostaglandin DP receptor antagonist. S-5751 inhibits cAMP generation in platelet-rich plasma induced by PGD2 with IC50 0.12 μM. S-5751 has anti-inflammatory activity. S-5751 can be used in asthma research[1].
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S-5751 | S-5751 is an orally active prostaglandin DP receptor antagonist. S-5751 inhibits cAMP generation in platelet-rich plasma induced by PGD2 with IC50 0.12 μM. S-5751 has anti-inflammatory activity. S-5751 can be used in asthma research. | |||||||||||||||||||||
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