2095432-38-3
2095432-38-3
Chemical Structure
MRL-436
- CAS No.: 2095432-38-3
- Formula:C24H22N4O
- Molecular Weight:382.46
InChIKey: YKCRQAHOVRYDKA-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CN2C1=NN=C2CC(C)C)NC3C4=C(C5=C3C=CC=C5)C=CC=C4
Biological Activity: MRL-436 is a RNA polymerase inhibitor with antibacterial activity. MRL-436 exerts its antibacterial activity dependent on residue 622 of the RNA polymerase β' subunit and the RNAP ω subunit. MRL-436 inhibits Rifampicin (HY-B0272)-resistant RNA polymerase derivatives and exhibits antibacterial activity against Rifampicin-resistant strains[1].
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MRL-436 | MRL-436 is a RNA polymerase inhibitor with antibacterial activity. MRL-436 exerts its antibacterial activity dependent on residue 622 of the RNA polymerase β' subunit and the RNAP ω subunit. MRL-436 inhibits Rifampicin (HY-B0272)-resistant RNA polymerase derivatives and exhibits antibacterial activity against Rifampicin-resistant strains. | |||||||||||||||||||||
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References
Keywords
