209984-57-6

LY-411575 Chemical Structure
209984-57-6

Chemical Structure

LY-411575

  • CAS No.: 209984-57-6
  • Formula:C26H23F2N3O4
  • Molecular Weight:479.48

IUPAC Name: (S)-2-((S)-2-(3,5-difluorophenyl)-2-hydroxyacetamido)-N-((S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)propanamide

InChIKey: ULSSJYNJIZWPSB-CVRXJBIPSA-N

SMILES: O=C1[C@@H](NC([C@@H](NC([C@H](C2=CC(F)=CC(F)=C2)O)=O)C)=O)C3=CC=CC=C3C(C=CC=C4)=C4N1C

Biological Activity: LY-411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), and also inhibits Notch S3 cleavage with an IC50 of 0.39 nM.

Cat. No. Product Name Purity Description Pricing
HY-50752 		LY-411575 99.28% LY-411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), and also inhibits Notch S3 cleavage with an IC50 of 0.39 nM.
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