2112731-81-2
Chemical Structure
N-(Azido-PEG2)-N-bis(PEG4-Boc)
- CAS No.: 2112731-81-2
- Formula:C36H70N4O14
- Molecular Weight:782.96
IUPAC Name: di-tert-butyl 16-(2-(2-(2-azidoethoxy)ethoxy)ethyl)-4,7,10,13,19,22,25,28-octaoxa-16-azahentriacontanedioate
InChIKey: QMUHVUPHHRSFNU-UHFFFAOYSA-N
SMILES: O=C(CCOCCOCCOCCOCCN(CCOCCOCCOCCOCCC(OC(C)(C)C)=O)CCOCCOCCN=[N+]=[N-])OC(C)(C)C
Biological Activity: N-(Azido-PEG2)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG2)-N-bis(PEG4-Boc) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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N-(Azido-PEG2)-N-bis(PEG4-Boc) | N-(Azido-PEG2)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-(Azido-PEG2)-N-bis(PEG4-Boc) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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Keywords