2158336-16-2
Chemical Structure
PD-1/PD-L1-IN-21
- CAS No.: 2158336-16-2
- Formula:C32H32BrClN2O4
- Molecular Weight:623.96
IUPAC Name: (4-((2-bromo-[1,1'-biphenyl]-3-yl)methoxy)-5-chloro-2-(pyridin-3-ylmethoxy)benzyl)-L-isoleucine
InChIKey: BCXBLLRCVRCSKX-BGOLNKOXSA-N
SMILES: CC[C@H](C)[C@@H](C(O)=O)NCC(C=C(C(OCC1=C(C(C2=CC=CC=C2)=CC=C1)Br)=C3)Cl)=C3OCC4=CN=CC=C4
Biological Activity: PD-1/PD-L1-IN-21 (Example 22) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-21 blocks PD-1/PD-L1 with the IC50 of 4.99 μM. PD-1/PD-L1-IN-21 can be used for the research of cancers, infectious diseases and autoimmune diseases[1].
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PD-1/PD-L1-IN-21 | PD-1/PD-L1-IN-21 (Example 22) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-21 blocks PD-1/PD-L1 with the IC50 of 4.99 μM. PD-1/PD-L1-IN-21 can be used for the research of cancers, infectious diseases and autoimmune diseases. | |||||||||||||||||||||
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Keywords
