2222727-47-9
Chemical Structure
Anti-MRSA agent 28
- CAS No.: 2222727-47-9
- Formula:C27H22ClN3O5
- Molecular Weight:503.93
InChIKey: UJVMMSCAZSNSEN-UHFFFAOYSA-M
SMILES: COC1=C(C2=C(C3=C4C5=C(C6=C(OCO6)C=C5CC[N+]4=C2)C=C3)C=C1)OC(C7=CC(C)=NN7C)=O.[Cl-]
Biological Activity: Anti-MRSA agent 28 is an antibacterial agent against multidrug resistant (MDR) gram-positive strains with MICs of 0.06-0.125 μg/mL. Anti-MRSA agent 28 can target DNA polymerase IIIC to reduce the amount of genomic DNA with the IC50 of 3.80 μg/mL. Anti-MRSA agent 28 has good antibacterial activity and reduces inflammation. Anti-MRSA agent 28 can be used against gram-positive strains and infectious conditions[1].
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Anti-MRSA agent 28 | Anti-MRSA agent 28 is an antibacterial agent against multidrug resistant (MDR) gram-positive strains with MICs of 0.06-0.125 μg/mL. Anti-MRSA agent 28 can target DNA polymerase IIIC to reduce the amount of genomic DNA with the IC50 of 3.80 μg/mL. Anti-MRSA agent 28 has good antibacterial activity and reduces inflammation. Anti-MRSA agent 28 can be used against gram-positive strains and infectious conditions. | |||||||||||||||||||||
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Keywords