222400-20-6
Chemical Structure
Tomopenem
Synonym(s): CS-023; RO4908463; R-115685
- CAS No.: 222400-20-6
- Formula:C23H35N7O6S
- Molecular Weight:537.63
IUPAC Name: (4R,5S,6S)-3-(((3S,5S)-5-((S)-3-(2-guanidinoacetamido)pyrrolidine-1-carbonyl)-1-methylpyrrolidin-3-yl)thio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
InChIKey: KEDAXBWZURNCHS-GPODMPQUSA-N
SMILES: OC(C1=C(S[C@H]2C[C@H](N(C2)C)C(N3C[C@H](CC3)NC(CNC(N)=N)=O)=O)[C@H](C)[C@@]([C@@]4([H])[C@H](O)C)([H])N1C4=O)=O
Biological Activity: Tomopenem (CS-023; RO4908463; R-115685) is a longer-half-life parenteral carbapenem. Tomopenem shows broad activity against 63 reference species. The activity of tomopenem against 293 clinical isolates is potent (MIC90, 0.06 to 4 μg/mL). Antianaerobic activity[1].
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Tomopenem | Tomopenem (CS-023; RO4908463; R-115685) is a longer-half-life parenteral carbapenem. Tomopenem shows broad activity against 63 reference species. The activity of tomopenem against 293 clinical isolates is potent (MIC90, 0.06 to 4 μg/mL). Antianaerobic activity. | |||||||||||||||||||||
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Keywords
