In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria

  • Antimicrob Agents Chemother. 2009 Jan;53(1):319-22. doi: 10.1128/AAC.00595-08.
Kaori Tanaka  1 ,  Hiroshige Mikamo ,  Kenichi Nakao ,  Taku Ichiishi ,  Takatsugu Goto ,  Yuka Yamagishi ,  Kunitomo Watanabe
Affiliations
  • 1. Division of Anaerobe Research, Life Science Research Center, Gifu University, Gifu, Japan. [email protected]
PMID: 18955522 DOI: 10.1128/AAC.00595-08
Abstract

The antianaerobic activity of tomopenem, a new longer-half-life parenteral carbapenem, was compared with Other carbapenems. Tomopenem showed broad activity against 63 reference species. The activity of tomopenem against 293 clinical isolates was potent (MIC(90), 0.06 to 4 microg/ml) and comparable to those of meropenem and doripenem and more potent than that of panipenem.

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