2225887-26-1
2225887-26-1
Chemical Structure
EGFR-IN-5
- CAS No.: 2225887-26-1
- Formula:C31H38FN9O
- Molecular Weight:571.69
IUPAC Name: (1-(6-((5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)amino)-2-((4-fluorophenyl)amino)pyrido[3,4-d]pyrimidin-4-yl)piperidin-4-yl)methanol
InChIKey: DXOUQSZKEPSXBC-UHFFFAOYSA-N
SMILES: OCC(CC1)CCN1C2=NC(NC3=CC=C(F)C=C3)=NC(C=N4)=C2C=C4NC5=NC=C(N6CCC(N(C)C)CC6)C=C5
Biological Activity: EGFR-IN-5 is a EGFR inhibitor with IC50s of 10.4, 1.1, 34, 7.2 nM for EGFR, EGFRL858R, EGFRL858R/T790M, and EGFRL858R/T790M/C797S, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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EGFR-IN-5 | 99.49% | EGFR-IN-5 is a EGFR inhibitor with IC50s of 10.4, 1.1, 34, 7.2 nM for EGFR, EGFRL858R, EGFRL858R/T790M, and EGFRL858R/T790M/C797S, respectively. | ||||||||||||||||||||
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Keywords
