1. JAK/STAT Signaling
    Protein Tyrosine Kinase/RTK
  2. EGFR

EGFR-IN-5 

Cat. No.: HY-111415
Handling Instructions

EGFR-IN-5 is a EGFR inhibitor with IC50s of 10.4, 1.1, 34, 7.2 nM for EGFR, EGFRL858R, EGFRL858R/T790M, and EGFRL858R/T790M/C797S, respectively.

For research use only. We do not sell to patients.

EGFR-IN-5 Chemical Structure

EGFR-IN-5 Chemical Structure

CAS No. : 2225887-26-1

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

EGFR-IN-5 is a EGFR inhibitor with IC50s of 10.4, 1.1, 34, 7.2 nM for EGFR, EGFRL858R, EGFRL858R/T790M, and EGFRL858R/T790M/C797S, respectively.

IC50 & Target[1]

EGFR

10.4 nM (IC50)

EGFRL858R

1.1 nM (IC50)

EGFRL858R/T790M

34 nM (IC50)

EGFRL858R/T790M/C797S

7.2 nM (IC50)

References
Molecular Weight

571.69

Formula

C₃₁H₃₈FN₉O

CAS No.

2225887-26-1

SMILES

OCC(CC1)CCN1C2=NC(NC3=CC=C(F)C=C3)=NC(C=N4)=C2C=C4NC5=NC=C(N6CCC(N(C)C)CC6)C=C5

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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C1   V1   C2   V2

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Product Name:
EGFR-IN-5
Cat. No.:
HY-111415
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EGFR-IN-5

Cat. No.: HY-111415